Category Archives: Uncategorized

There are resources and databases for so many things popping up that it’s impossible to keep track. This new one SYNGO is something I would have found really helpful while constructing a manuscript last year (I looked everywhere for something like this!) But it’s in perfect time to help a new collaborator at UVA. StudyingContinue reading “SynGO — A beautiful resource for neurons and synapses and stuff!”

It’s 2019….and I’m shocked that this even needs to be said to anyone, but it does. I know it doesn’t have to be said to the brilliant people who, for some reason, come to this blog to read my rambling about proteomics, but — hey — maybe my annoyed rambling here will actually be usefulContinue reading “Transcript Abundance IS NOT THE SAME as protein abundance!”

The XlinkX nodes that can be demo’ed/purchased and ran in Proteome Discoverer 2.3/2.3 (I need to look to see if I have them in 2.4…which I don’t have on the PC I’m typing this on) can seem to be a bit of a black box. It’s even more apparent when you’re troubleshooting or trying toContinue reading “Great quality Youtube video — XlinkX driven XL-MS studies”

It is completely possible to prep a sample, run an instrument and process your data without ever knowing at all how any of it works. And that’s fantastic — until something goes wrong. On the data processing side so many things are just assumed based on 15 or 20 years? of work developing this stuff.Continue reading “Great tutorials on FDR and Parsimony!”

….this new manuscript might have the answers to a lot of the questions I think we’ve all been hearing, primarily…. “HOW DO YOU INTEGRATE ALL THIS “-OMICS” DATA!!?!?!” I’m going with “might have the answers” because there are a lot of assumptions made by the authors regarding the math background of the reader. When youContinue reading “Proteome + Metabolome + Immunome + Microbiome + Transcriptome Integration = Pregnancy Multiomics!”

I don’t know about you but I’ve been very disappointed every time I’ve used any kind of a protein motif software tool….awesome…now…I’ve got a bunch of letters that are funny sizes and colors. MotifeR may be what I’ve been hoping this motif stuff would do! There is a cool online web portal (looks like aContinue reading “MotifeR — Better than just funny letters that are the wrong size!”

….does this deserve an extra post? Probably not, but I was on a PC without adblockers enabled and — an ad suggested in 3 images why I should drop…I dunno….about a million bucks on the newest mass spec….I mean…I wasn’t in the market…..but….

Não se passaram nem três dias em que foi ao ar a ‘matéria’ do Fantástico sobre os Arautos do Evangelho, e já começa a desmoronar uma das principais acusações que o programa apresentou. As deturpações do grupo organizado que ataca os Arautos poderiam ter ficado restritas ao Ministério Público e tribunais, mas eles preferiram seContinue reading “Mensagens revelam falsidade da colombiana do Fantástico”

What’s all this talk of metaproteomics anyway? How does it play in with “microbiome” buzzword everyone keeps rambling about all over the place? This may be the ultimate guide to where we are right now in applying proteomics (and genomic) technologies to understanding the micobial community (microbiome) in the human body. We might be, byContinue reading “Current understanding (and challenges) in Human Metaproteomics!”

If you haven’t seen this new editorial in Science, you should 100% check it out. MINIProteins? You mean the ones that all of us could do and feel like experts in TOP DOWN PROTEOMICS?!?!  Sign me up! 50 amino acids? That’s 5-6kDa. 1) That’ll separate nicely on C-182) I probably just have to run itContinue reading “New Universe of miniPROTEINS is upending cell biology!”