Category Archives: Uncategorized

Okay — I now have a PrecisionFDA account and I’ve just uploaded data to it, and I’m trying to reduce some spectra with RIDAR with it — and I have no idea why this is here, but I like it. Disclaimer: Since this is an HHS US government thing it might be for US peopleContinue reading “Precision FDA — Free super computing power preloaded with applications!”

O prefeito Clébio Pavone enviou à Câmara Municipal de Quixeramobim um projeto de lei do executivo que cria o “Cartão do Bem”. A proposta foi o principal assunto desta quarta-feira, 20/11, quando ocorreu a sessão ordinária na casa legislativa. Os vereadores rejeitaram a urgência simples e acataram o projeto que segue agora para a ComissãoContinue reading “‘Benefício social’: Câmara recebe projeto da Prefeitura que cria ‘Cartão do Bem’ em Quixeramobim”

About darned time! Just accepted at JPR — the first (as far as I’m aware, please correct me if I’m wrong, study showing the use of TMTPro (previously TMT16-plex)! Quick summary of my rapid readthrough: 1) This group typically uses NCE of 38 for TMT10/11-plex reagents, they use 32 for TMTPro (please keep in mindContinue reading “A wild TMTPro Paper has appeared!!”

A long time ago I was in a relatively serious car accident. My recovery cost me two weeks of classes and I learned that concussions are seriously no fun at all. However, if you gave me an option of going through that again or migrating all my computers to Windows 10….I’d need time to thinkContinue reading “ThermoRawFileParser — A big little step away from Windows!”

Ummm….okay…so this is open access and it addresses one of the biggest (and scariest) elephants in the room. I hate to keep drawing attention to it, but with 40+ peer-reviewed studies on forensic proteomics in 2019 already, we need to start talking about this. Anyone in the world can go to ProteomeXchange and download dataContinue reading “Re-Identifiability of Proteomic Data and its Implications….”

If you need to catch up on a ton of those genetics terms and techniques you’ve heard people mumbling about, there might not be a better or more interesting way than this new documentary. CRISPR stuff?  Check! GeneDrive stuff? Check!Some…interesting….looking “Biohacker” guys saying reasonably accurate science things and then injecting themselves with stuff?

I think I just successfully convinced @SpecInformatics to throw in on a study where we try to do ALL THE PROTEOMICS THINGS on High Performance Computing. I just got 100,000 core hours for free, and I was told that if I could come up with a valid excuse I could probably have another 300,000 hoursContinue reading “What to do with 100,000 core hours of super computer access!??!”

Have you seen the great new application study where GalaxyP was used and thought…okay…. The arguments are building up for why you need this. Proteogenomics?TAILS?MetaProteomics?Secretomics? If you’re also thinking “…wait…remind me what Galaxy is again…? I know I saw a talk from that really cool guy from Minnesota (Pratik)” Galaxy is a flexible interface forContinue reading “Great GalaxyP Tutorials hosted at GalaxyProject.eu”

This article isn’t brand new, but I just stumbled across it and really appreciated the perspective on it. It’s open and available here. 1) How do you get funding to set up and run a core outside of where most of them are?2) What challenges would you face if you packed up and decided toContinue reading “Challenges and Opportunities for Mass Spec cores in the Developing World!”

How we deal with “missing values” may always be controversial and I’m going to assume that no level of improvements in mass spectrometry engineering is going to be able to fix this. Sure, we can get better coverage, but sometimes that peptide just isn’t going to be there — maybe because it’s a got aContinue reading “ProtRank — Go beyond protein value imputation!”