Se da mesma forma os Milicianos colocaram regras dentro das comunidades do Rodo e Antares em Santa Cruz, cobrando taxas para melhorar as condi��es da comunidade (segundo ele), da mesma forma os roubos desagradam os moradores. Segundo informa��es, nos �ltimos meses alguns com�rcios no Antares e Rodo, foram assaltados na comunidade, e alguns saqueados naContinue reading “Os roubos aumentaram na gest�o da Mil�cia em Santa Cruz”
Author Archives: Susann Lees
TCP invadiu territ�rio do CV em S�o Gon�alo
Ainda no primeiro dia do ano, as guerras entre fac��es voltaram acontecer em S�o Gon�alo. Segundo informa��es, os traficantes do Terceiro Comando Puro (TCP) do Complexo da Alma, foram invadir a comunidade do Bichinho em Sacramento, tamb�m em S�o Gon�alo. Foram duas horas de intenso tiroteio dentro da comunidade, gravado e relatado pelos moradores. PareceContinue reading “TCP invadiu territ�rio do CV em S�o Gon�alo”
TCP invadiu o Jorge Turco no meio do baile
Ano de 2020 come�ou com a primeira invas�o na cidade do Rio de Janeiro. Os traficantes do Terceiro Comando Puro do bonde do “Sem Mem�ria”, entraram no Morro do Jorge Turco em Coelho Neto. Segundo informa��es, foram no momento que estava acontecendo um evento na comunidade, e mataram 2 pessoas. CV optou por fugir doContinue reading “TCP invadiu o Jorge Turco no meio do baile”
Optimizing/reducing in source fragmentation on 3 different Orbitrap systems!!
Talk about a useful study! If you’re doing tryptic peptides, maybe this isn’t all that useful, but if you are working on anything that is more fragile than that (glycopeptides? PARPylated? intact/native, metabolites…we could go on an on here) this is probably worth at least thinking about. On the letterbox systems (the ion tranfer tubesContinue reading “Optimizing/reducing in source fragmentation on 3 different Orbitrap systems!!”
Urinary Peptidomics Reveals Diabetic Markers?!?!
Well — if you needed a protocol for doing urine peptidomics, all the way down to standardizing everything to the urine creatinine levels (90umol, if you were wondering) and wanted some WTFourier level proof that this is a good use of your time, may I present: 1) I didn’t know urine peptidomics was a thing2)Continue reading “Urinary Peptidomics Reveals Diabetic Markers?!?!”
PISA — Multiplex Thermal Proteome Profiling!
Want to massively increase the speed of your drug mechanism elucidation/ drug target workflow? Back your bags for PISA! Nope. Not that one. This one! Proteomics Integral Solubility Alteration! (PISA is a much better name). What’s it do? It multiplexes Thermal Proteome Profiling — in the context of drug treatment. Here is a post thatContinue reading “PISA — Multiplex Thermal Proteome Profiling!”
The Case for Proteomics and Phosphoproteomics in the Clinic!
After a couple of days of somewhat successfully skirting any discussion of politics with my family for the holidays – with one extremely notable exception, I’m so pumped to type something that people with a similar mindset might read one day. What about this for building some consensus? Where are we now? What are theContinue reading “The Case for Proteomics and Phosphoproteomics in the Clinic!”
PeakOnly — Deep learning Python code for finding your MS1 features!
There are a lot of ways to find compound peaks in your data, but some compounds/peptides (particularly modified ones) just have lousy elution profiles. Sometimes you just have to go in and look yourself. Isn’t that what all this AI/Machine Learning/Deep learning baloney is supposed to be doing for us? Automating tasks that are aContinue reading “PeakOnly — Deep learning Python code for finding your MS1 features!”
Your Holiday Gift from MCP is a special issue on ProteoGenomics!
Okay — it says it was online in August, but this is the first time I’ve seen it and MCP’s Twitter just showed this crazy cool cover from http://www.brushwithscience.com You can check out the full special edition here. I’ve rambled about ProteoFormer on here before. (RiboSeQ + Proteomics data analysis) MetaQuantome deserves a revisit later.Continue reading “Your Holiday Gift from MCP is a special issue on ProteoGenomics!”
R2-P2 — The robot method that’ll make large scale phosphoproteomics realistic!
Try forgetting the name of this great new method (you’re welcome! this is the kind of stuff I contribute to society)! And if it brings some awareness to a fantastic new study that shows some demonstrates a way to fix several of the fundamental problems in my field, then it’s worth it to me ifContinue reading “R2-P2 — The robot method that’ll make large scale phosphoproteomics realistic!”
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